Doxa, I am sorry to read this. With multiple lesions, quickest response would obviously be ADT combining Lupron (probably) with one of the next generation medications. One anecdotal note: on my last...
JAMA reports a meta analysis reveals a twofold incidence of all CV (cardio) events associated with adding the newer generation of ARSIs to standard ADT. ARSIs include heavy hitters like Zytiga and...
“Favorable intermediate category?” I am not sure I would ever want to use the word “favorable” with respect to cancer. Nothing favorable about it. You have been very diligent with your urologists,...
Prato, In the last month my wife and I know six people who have come down with COVID. One 77 year old woman friend seemed impervious, always on the go, until she went to a wedding in New Jersey. She...
Prato, Congrats. Doing great. I am up for a three month draw at the MSK mother ship in Manhattan in two weeks. Get results in an hour or so as the draws are whisked by pneumatic tube (remember...
How do we know if 81’s entire post was not generated by his AI? I an thinking of delegating all my written coms to my AI avatar, known heretofore as NewspaperLover-2.1 (2.0 had a few flaws, unlike...
Recently read about an astonishing discovery at an ancient monastery in the mountains of Romania. The order of monks is nearly 1500 years old. The Rules of the Order have been handed down unchanged...
Great stuff, 81. I love this… Bill...
Since failed surgery in ‘09, I have had three distinctive rounds of ADT: in ‘11-‘12 as part of a salvage job, and in ‘21 and ‘23, always with Lupron in the fore. I have not experienced any untoward...
Your age works for you. I have a friend who underwent surgery at about your age. It took over a year, including Viagra, but he got it back. Wish you well… Bill...
BillyBob, The intermittent ADT described by mattam above in the EMBARK trial is me, real time right now. My MO placed me on the EMBARK ADT schedule last April, adding one month of Firmagon up front...
Hi Prato, Imperfect in terms of all mortality with associated PCa, but I am certain I would be long gone without the early warning system of PSA. Another consideration is that many forms of cancer...
Steve, Thank you for keeping us so well informed. We all hope that you can join the Actinium trial, and that results will be good. You are one of the stars for us long haulers. Best wishes…. Bill...
Mattam, Yeah, me too — born 12/02/1943. Extra month was nice. But when I have to scroll down forever to get to 1943 to indicate birth year on the Web for something or another, I’m thinking This Can’t...
Hi Mel, PSA rise upon stopping the Ogo should by itself not indicate resistance. Been my pattern for near a decade. If you want to do a PSMA scan for possible mets, recommend Gallium as opposed to...
Mc, Some solid histories already posted on this thread weighing experiences with both radiation and surgery as initial responses. As noted, it is a personal decision. I would add one thought. There...
A lot to discuss here at home. Me a Gleason 8 PCa patient starting 2009; my wife a triple negative BCa patient since 2003. Me, a patient at MSK since 2011; her, a 21 year survivor of triple negative...
So herself and I are currently doing a three week walkabout in England. Love Europe in March, as so many pleasures are indoors or at comfortable outdoor cafes. Also hate hot weather. London has been...
Hello Doxa, Sorry you and your husband have to be here. His history and mine are similar, DaVinci, followed by Salvage, now an imaged met years later. He and I started about the same time. In 2022 I...
PaxNova, If you can, on your next PSMA PET, gallium, as opposed to F-18, is now state of the art as an imaging agent. Nothing better than gallium — also you do not have to fast… Bill...
Hang in there PAX. Our histories and situations are remarkably similar, except I am older, though no wiser… Bill...
Halbert, Well written and a vital distinction… Bill...
JPS1, I transferred my case over to MSK in the fall of 2011, and have never looked back.That is 13+ years with a Gleason 8, and I am still there and very much alive. No miracles, but huge advantages...
I did a total right hip replacement while on ADT. My surgeon asked that my MO sign off, but that was it. Surgery and recovery time went great. Happy replacement… Bill...
Galileo, Good of you to drop in. Keep hanging in and hanging out. Best wishes… Bill...
Great that the Gleason remained steady, but I have also come to appreciate over the years that Gleason is not quite the whole story with PCa. The problem is that for myriad reasons, or for no...
Famed prostate cancer pathologist Jonathan Epstein has resigned from Johns Hopkins. He had been placed on administrative leave last year for unspecified reasons. For many years, and for many men on...
I’ve noticed a loss of distance in what used to be my favorite body part… Bill...
The food chain being as it is, all food is plant based, or going further, photosynthesis based. Herself and I eat a Mediterranean diet, which includes seafood and some poultry and red meat. But not...
Always good to be thankful, and maybe alert. I had right hip replacement surgery in the summer of 2021. My left hip had the same done in 2007. A got a little happy medicine before being wheeled into...
Jr, Sorry you had to join us. Seeds? You may want to weigh that approach against external beam radiation. Brachytherapy has been on the wane in recent years as external beam options have been...
hrpufnstuf, I use low dose Xanax also as the need arises, only occasionally, only at bed time — it helps eliminate those 3 am anxieties about PCa, that keep me awake, and have no resolution in the...
F-18 technology is good, but Gallium is state of the art — that is more sensitive to smaller mets. Gallium is the most sensitive technology available....
Great news.! Happy for you… Bill...
Even at this level of PSA, there is a good chance a PSMA may return nothing. Does not mean it is not there, of course, just that it cannot be imaged with the best tool we have. A very possible...
JPS, Great job moving ahead on several fronts at such a tough time. To my thinking the PSMA scan (hopefully Gallium) will frame your treatment decision options in the near future. I have been with...
JP, I have a friend who was diagnosed with a Gleason 7 at age 48. He just turned 72. At the time of his diagnosis, treatment options and diagnostic tools were far more limited than today. Yet he is...
JP, So sorry for the bad news. If next step is a PSMA, recommend the Gallium imaging option. Most sensitive imaging available, as far as I know. Wish you well… NewspaperLover, Bill...
Prato, Seems like yesterday when you boarded this ship. Congratulations on your continued treatment success, and thanks for the hard work you do for this Board. Wish you Health and Joy in the New...
JPS2, The limitation of MRI is that it cannot provide a definitive Gleason score. Only a tissue sample, a biopsy can do that. Gleason is not destiny, but is a terribly important gauge to determine...
Thanks. I am finding the same problem....
Too Young, Yes the met was treated with standard 5 SBRT sessions in Sept ‘22. Well, these things don’t just get zapped and disappear Star Wars style. So some remnants still there. Hopefully mitosis...
Too Young, PSMA may not show anything at your levels. I had a somewhat similar linear pattern lasting nearly four years starting in Jan ‘15 and rising from .06 to 19 and some change before MO began...
Great news! Happy for you. Gives us long haulers hope for the efficacy of this treatment. Best wishes…. Bill...
After 13+ plus years at this, have lost much of my body hair. I once observed to my wife that she had more leg hair than me. You can imagine how well that went. Didn’t restore the bling to my crown...
So after seven months down the well trodden path of Degarelix /Lupron/XTANDI my MO has instituted a Pause. Treatment took PSA down from 18.6 to .19. Evaluate in three months. Last round of ADT lead...
OK Golfer, You have already received some very thoughtful replies from members on this Board. I think the best thought I can add is that I was diagnosed with a Gleason 8 in 2009 and I am still here....
Trailguy, Very difficult and troubling SE. Glad that you are feeling better and that PSA remains well contained… Bill...
Msttam, Great news as I am a relatively new X man, combined with 3 mo Lupron. Have had very good results. When I met with my MO in April to discuss systemic treatment, I asked his views about Zytiga...
Thank you Mattam. Clarifies. At 79 I rather am intrigued by a T level of 3,000. Not even in my horniest teenage days… Bill...