I imagine this development has been discussed, but I couldn't find anything in a search. This seems like really exciting news, assuming the test is reliable, easy enough to use, and inexpensive...
To clarify, I haven't tried oral mesalamine for a while. But last time I did, I received no benefit. My colonoscopy showed inflammation-free rectal and sigmoid (attributed to daily mes. enema use),...
I wonder if anyone can relate to this. Mes. enemas have always done a pretty good job of keeping my lower inflammation in check. My I still have inflammation in the descending colon that the enemas...
I can't really comment on having an eating disorder, as I never had one, but I can relate to having a host of negative feelings about my body as a result of this condition. It's depressing to know...
Mike, not to hijack the thread, but what are your current symptoms? How do you treat them and have you tried all biologics? Would you consider surgery? Just curious...
Thank you! How long did it take for the sulfasalazine to help your condition? I've tried asacol and colozal, neither of which helped....
Thank you for the replies. I tried sulfasalazine a while back, but had to stop because I was getting headaches. Might be worth revisiting. . ....
6mp I believe, which didn't help at all. I also tried Uceris when it first came out. Provided zero relief, so I'm thinking steroids just don't work for me....
Hello, I'm on Simponi and rectal meds. Simponi had me in 6 mos remission, but now I'm bleeding and in discomfort for a week. I tried pred (40 mg taper) 3 years ago. It helped for about a week but...
Very interesting, Mike, thank you! I don't understand most of the science, but I have taken Remicade before with no effect, so I'm surprised that any TNF suppression from these low dose meds could...
As the subject says, a week ago I discontinued these two meds that I took for UC symptoms (primarily abdominal pain, went away 4 months ago). During the last couple of months I've developed some...
Thanks vangirl for the reply! And thanks Serenity for the bump! Vangirl, I really hope you get better soon. And my fissures have gone the same way: it seems like they're improving, and then they...
Anyone? Thanks....
Hello, Anyone who has had these before knows they cause a lot of discomfort and are somewhat demoralizing. My doctor found a few different anal fissures in me a couple of weeks ago. He prescribed me...
Man, I've been doing quite well lately, but I missed a dose of my mesalamine enema and suppository, and today I saw specks of blood and am in discomfort... Can one be in this tenuous of a remission,...
Good questions Scott. My quality of life now is around a 7.5 or 8. Before Simponi, I was around a 6. So improvement is definitely there. It's more a question of whether I still have lingering...
I've had slow improvement ever since going on simponi about 5 months ago. I still have some discomfort that comes and goes, but it's a lot less pronounced than it used to be. Stools are also usually...
I agree with you there. However, the cure I'm referring to would be a universal one. Anything else wouldn't be sufficient to reap the reward. And though a universal cure may be unattainable, we won't...
Here's a hypothetical, What if we and numerous others were able to donate money to a fund. At any point, those who donated money could choose to be reimbursed (unless of course the cure is...
Wow, sorry to hear that geeker. Are you being treated for this residual pain at all? How do you manage? The off and on pain of this disease (even though I'm fully functioning) makes it tough to stay...
Not sure if I'm in remission, but my doctor thinks I am be based on a calprotectin test. I still experience intermitten pain and discomfort. My stools seem to get a little less form during these...
My intestinal pain has been pretty minimal these last couple days. However, today I came down with a head cold, and when I put the patch on I became increasingly dizzy/anxious. I just took it off....
I don't see anything wrong with that. It should come out with the fleet enema....
I think I'm somewhat similar to you guys. I've been taking mes. enemas nightly for over a year. I suffer with discomfort on a regular basis, but don't have any bleeding unless I start to ween myself...
I started my first 14mg patch last night. Boy did I have vivid dreams! It was kind of a turbulent sleep, and I do feel sort of hung over today. Not too much pain today. Here's hoping!...
Additionally, I feel for you. I'm in pain all day with my colon, but at least I have it, and perhaps surgery could relieve the pain for me one day. I'm sorry surgery hasn't worked for you thus far....
miserable4life, I'm sure you already know this. But to get through difficult times still standing, one has to foster as positive an outlook as one can muster. One must be strong and hold onto hope....
Could nicotine help someone who has never smoked before? I have a lot of intestinal/anal pain but never smoked cigs before. Wondering if nicotine could help me achieve remission. Thank you....
My last flex sig was last Spring. It revealed a 30cm patch of inflammation. Thanks for the response....
A calprotectin test revealed no inflammation. However, most days I have constant achiness in my rectum/left side. I also have abnormal bm's (loose or constipated). I'm on simponi and mesalamine...
Is there any new news on its release date? Have any of GI's talked to you about this?...
Well, good luck. I'd be interested to hear how it goes. I've been on the 20mg for about 2.5 weeks now, with no side effects (maybe a little drowsiness)....
Yes, for sure. Is Elavil helping you at all? I think my pain level is about the same on it, although I had a tiny bit of bleeding, which makes me think my symptoms may be the result of inflammation,...
And perhaps I'll do some digging online for one too. Good idea....
poopin, Thanks so much for your reply. I'm glad to hear you've had a positive experience with a psychologist. I hope for the same....
After spending literally all day worrying about my condition and feeling down in the dumps, I've decided I need emotional/mental assistance from a professional. As the subject says, has anyone had...
Yes, which is what I was using. Goddamn, I let this disease put me in a foul mood too often. Anyone else have thoughts? Thank you....
Miserable4life, Thank you. I'll look into this, but this is the only day I've had this bleeding in a long time. I don't expect it to be a persistent problem going forward....
Ha. No i'm not. This is why I'm concerned......
No. Not sure what those are for. My question is simply, does wiping too hard ever cause specks of blood. Or is this more likely a sign of lower inflammation?...
Just when I thought I might be in a solid remission (still experience discomfort, but no bleeding in a long time), I wipe my bum and see specks of blood on the toilet paper. I wiped it kinda rough....
Yo yo. Sounds good. Umm I can't say whether I have IBS or not. I have a history of anxiety manifesting itself as pain in different areas of my body (headaches, shoulder pain etc.). I'm not sure...
Hello! My GI prescribed me this about a week ago for the similar issues (abdominal and rectal discomfort, despite having no bleeding or high frequency). From what I've read, it's a good idea to try...
Have any of you experienced residual symptoms even after the urgency and bleeding subsided? My GI thinks a colonoscopy would reveal a healthy colon in me because the calprotectin test I took was 53...
I'm still take 1 mesalamine enema and suppository per day. I think it keeps the sigmoid/rectal area mostly in check. Besides that, just supplements (l glutamine, fish oil, vit. D, probiotics)....
Summer, huh? Ugh. . ....
Thanks for the info, and I'm glad you're managing well. I am a little concerned that you say you're eating very small amounts, and experienced mal-nutrition in the past. Maybe I'm wrong in doing so,...
Thank you all for the replies. First of all, I was directing my earlier comment at Gary. I must have been forming my reply when you replied, itsalwayssomething. Woofwoof, no hard feelings. Perhaps I...
Good luck with the Simponi! I have similar symptoms (abdominal and rectal discomfort) and have been on simponi for 4 weeks. Not sure if it's had any effect (positive or negative) thus far....
So, is there any indication when this drug will be on the market?...