Really well written, Thanks!...
Silver has been discussed here from time to time. There is some evidence it has antibacterial properties. Except for infectious colitis, the need is for anti-inflammatory or other immunomodulator and...
The link I posted says 80 small / 20 large....
Yes. You are right. They generally have a monthly cap as well as the $5 min. So if the cap is $500, they pay $495. If the copay is full price because you are in the deductible window, then you still...
The real issue is how much elevated risk of colon cancer comes from the inflammation. I do think trying to end it with more mesalamine is a logical 1st step good luck...
While the final absorption of water that produces solid stool occurs in the large intestine, a lot of fluid is normally absorbed in the small intestine. The link below says 80%, and it occurs by...
force as much water as you can...
What country are you in? Moving up the med ladder is common in the US. The meds you are taking is not preventing the inflammation. For a few people with food intolerances, elimination diets can help....
Also, all probiotics are aerobic. Nobody is making probiotics with anaerobic strains. Likely those are what will really make a difference. I do think in the future probiotics or other gut microbe...
I don't know about the # on the pill, but the NDC code on those two labels has 476 only in the brand name label. The generic label has a 100. It does seem odd that the new pill went to flare in 3...
How do you know inflammation is not going down? A blood test? From a scope result? OR jsut because some symptoms remain. No bleeding and solid stools sounds like remission or near-remission. Why do...
If there was bloody mucus - the issue was never "only constipation". It seems worth a try to see if the enemas help. Mesalamine is a low-risk drug - especially as an enema. And, you have used it...
With things so quite, there could be benefit form a probiotic.It is a bit hit-n-miss unless you have a profile of the gut microbes, and some idea of what you want the probiotic to change. Then you...
I think when considering "illness" it is important to consider symptoms and inflammation separately. THC and help with appetite and maybe slow motility. CBD has anti-inflammatory properties and could...
Well the put parthenogenesis in the title, but only review studies of maintenance. Also, they focus on triggering symptoms, and not triggering inflammation/flare. The finding about improved symptoms...
I think you have it wrong. Possibly the science writer led you astray. The primary effect of the drug is to target a chemical messenger in the immune system. All of the biologics either block the...
I think it mostly means that your aerobic species are down in population. The positive down from heavy to moderate, and the negative down from heavy to absent. This could indicate dysbiosis, but...
This is pretty useless? Is it satire? One comments on this forum about vaccines messing with immune system in a way relevant to autoimmune disease were uninformed and overly broad. There are a...
Hmmm. It seems to indiscriminately destroy the B-cell that comprise the immune memory. This results in general immune suppression. But, if they way it kills B-cells could be harnessed to kill only...
hard to pin it on prep without a plausible mechanism. not clear how a prep would make a permanent change in the function of your muscles. maybe you were low on some useful gut microbe and the prep...
joint pains can accompany UC, but if you are in remission less likely. you can get some joint pain or muscle ache form mesalamine, but usually not suddenly after years. you could call in to your GI...
Usually the recommendation is for the whole colon. Mostly the colon absorbs water. Maybe some vitamins in the right colon, but most nutrients are taken up in the small intestine. I have heard of...
they have not been around since 8/10/2017 11:01 AM...
It does seem early days to suspect a flare. Seeing the NP sounds OK, but just don't let them "assume" it is a flare and start something that might have side effects. Try to be very sure it is c-diff...
I had infusions because I did not want *any* more symptoms. But they can be expensive. If you need oral, you need to find a kind that is bioactive (readily absorbed), has few side effects (especially...
if pathology confirms you are in remission, then other sources of your GI symptoms will need to be sought....
Good thought about him not knowing the software he was using. Quite possible the software was updated, and he was clueless....
The literature notes some people get a great response to 1st line drugs and have long remissions. Others get an incomplete response and climb the drug ladder. Some eventually get well managed - and a...
It is interesting to hear about a new way to eliminating bacteria. RIght now this is not so strongly related to diabetes or UC - the science journalist seems to have failed at understanding the...
glad to hear the pharmacy has it ready. I just don't see any way your insurance can have a pending prior approval request AND you pharmacy have not even gotten the prescription. So either you doc...
The prior approval for anything, procedure or drug, is at the discretion of the insurance company. There are no government regulations or laws about prior approval.The are some laws about controlled...
It is important not to miss the point that inflammation in itself, it a normal, healthy, and necessary part of the immune system. The problem is dysregulated inflammation, where signals to inflame...
The one recent study I read showed much larger effect than others, but it was neither single or double blinded. I looked now and then at new reviews, and they all underscore the potential of...
With you low level symptoms, it does not make a lot of sense to test broadly until the UC has been visualized. IF inflammation is found that can explain the bloating, then treat that. IF you are...
Generally it is not possible to fill a prescription written in another country. Unless Australia and Canada had some reciprocal agreement. If you don't bring meds (as ipoop suggests), you would have...
Hmmm ... points #2 and #3 have some merit. The genetic risk is not the most solid reason to avoid children. But #1 is just ignorant. It is so definitely conclusively proven that genetic...
Inflammation is certainly one source of urgency. But motility issues (including spasm) can also produce urgency. I suspect that while holding bowel movements can induce constipation for some, it can...
It is interesting. It does not say much new when it notes that gut microbes getting through intestinal barrier is associated with chronic diseases, including auto immune. They also note that the...
This is good work. The specific processes and the extent of colonization needs to be understood if it is ever going to be figured out whether dysbiosis contributes to UC, or UC produces dysbiosis....
You did not mention which meds, so you post is of little value and had great disruptive/conspiracy potential. You don't even consider that you got relief form a minor side effect of the meds and...
I think the risk from anesthesia is additive not multiplicative. This mean if there is a .02 chance of complication each tiem and you go 3 time it is a total of .02+.02+.02=-.06 total, although the...
Possibly you can resume at a lower dose - especially if you have lost weight. Possibly the effect can be manipulated with allopurinol. Currently you are failing Imuran because of a potential side...
it is possible it was not a flare, or that you nipped it early with probiotics. It is also possible (although less likely) that it just went away because spontaneous remissions are seen in the...
Potential effect of mesalamine on kidney is rare, and for topical rectal administration should be negligible unless you have unusual sensitivity. It is not clear to me why you are seeing more fluid...
I heard this this morning too. I thought of this group, and other collections of friend that pursue diets purged of one ingredient, or seek food purity in some fashion. While it is not pathological...
it is intended for life (or until it stops working). There is some research on using biologics as short-term rescue drugs, and then discontinuing - but there is currently no standard of care saying...
This is my understanding too. Having UC is not a large risk for PSC. Having PSC is a big risk for also having UC. If your liver and kidneys have not shown consistent elevation in past tests, any you...
Do you mean a Canadian pharmacy or something? Any US mail-order pharmacy uses licensed pharmacists and the same prescription drugs as brick and mortar.Most insurance companies have their own mail...
CT can show thickening consistent with colitis or UC, and with other symptoms and medical history of UP, it is a good guess that this is UC pancolitis. But only biopsies can confirm that. IF crypt...
They should be able replace or revive the voided prescription. Even if the doc had to send another, it should be filled because already approved....