I'm sorry for the nausea: it is one of the worst side-effects to endure. Keep hanging in there. What you are doing is an act of love that can eventually help thousands of people who are searching for...
Please let us know. I have read a lot about Obefazimod and have high hopes for this medication. Tonito...
Bacon Girl, Yes, Rinvoq does raise your lipids. My GI warned me of this before starting. However, my general doctor put me in 5 mg. of Crestor (that's the lowest possible dose) and my lipids went...
Skyrizi (or Rizankisumab) is probably the best and safest. Dr. Marla Dubinsky (Mt. Sinai, New York), one of the leaders in IBD in the world, has said that "she would shout from the rooftops until she...
I'm so sorry. Have you considered going to hospital? The symptoms you just mentioned are very severe. At hospital they can check for C. Diff. Prayers your way....
For me at 3 days I was having no blood and solid stools. It truly was/is a miracle drug for me. But I also think that since I started Rinvoq while Humira was still in my body, I was basically doing...
Ditto to Sara's comment above; the difference is that I take Rinvoq. By the way, you mentioned blood sugar. That is not from Rinvoq but from prednisone, which is notorious for raising blood sugar and...
I'm sorry to say this, Bacon Girl, but one of the great advantages of Rinvoq is that it does tend to work very fast. For me, in three days it was already working. Here is a possibility to discuss...
You can actually return to the 45 mg. induction strength if you flare at 30mg. This is more effective and safe than using prednisone either oral or rectal. That is the point of the poster I pasted...
Here is a look at an interesting Poster from DDW 2022....
Hugo, Just out of curiosity, do you get sick more often (e.g., upper respiratory infections) since you've been on the combination therapy? I hear a lot of GI's (e.g., Dr. Bruce Sands) saying that...
Sorry you are in the hospital, Holly. I hate being there. I would definitely try Rinvoq. From what I have read, there was disappointment on the effectiveness of Filgotinib (Jyseleca). Rinvoq has...
Carter, see my different posts on it. I started to flare after being on Humira monotherapy for five years. I started to develop antibodies and a Fecal Calprotectin test was 6580! My GI wanted to add...
I only had to fail one biologic, i.e., Humira (and in fact I did not 'fail' it. My GI thought that if we added immuran would could wipe away the few antibodies I had built. But I refuse to take...
Major Rad, See my report on Rinvoq, which I just posted....
Well, After 6 months on Rinvoq 30 mg. I had a colonoscopy with the following results from my doctor: Below are the results of the biopsies from your recent colonoscopy. Diagnosis A. Sigmoid...
Nakamura, I'm sorry about your son. My own son is 11 and he has UC as well. I know how difficult this can be. My son was placed on Remicade after about 3 years of ups and downs. His doctor did not...
I know that Rinvoq is not recommended during pregnancy, and Xeljanz and Rinvoq are cousin drugs. So I'd be very careful and first ask the doctor....
Congratulations Sara! I hope the Xeljanz keeps working for a long time....
Pam, If you are concerned with 6MP and liver problems and cancer (and this medication has caused cancer to some: I know of one excellent doctor and researcher, Marla Dubinsky at Mt. Sinai in NY, who...
I had C.Diff and 14 days of Vancomycin healed me. It's a safe and effective antibiotic....
Dear Pam, I had very similar symptoms to yours for my UC for a number of years. Then I got to the point where mesalamine (both rectal and oral), although helping my UC, was not putting me in...
Agreed. That's the point....
Since when is "pedantic" the same thing as clear and specific? Writing a post with respect --but carefully and detailed--is not pedantic. I don't think we move forward the discussion by using the...
I was on Humira for 5 years. At times I would get sick (sore throat, cold), but not more than the person who was not taking Humira. All in all, biologics are actually very safe medications. I feel...
Thanks for the update, Sultan. Glad to hear we may have another mechanism of action in the armamentarium....
Quincy: I respectfully disagree with you. UC does not always start at the rectum: for some people it starts at the caecum. In addition, if your disease is concentrated in the transverse colon, how is...
I am sorry you are struggling, Jess. This disease is tough at all levels, including the psychological. Mesalamine enemas can be very effective if your disease is concentrated on the left side of the...
Thank you for the information, Sara and Paduk. Appreciated....
Overall it's good news. I think any time we get a new medicine with a different mechanism of action is good. My understanding is that the safety for this medicine is great. It is like Stelara, except...
Hi poopydoop: I would recommend you watch this short video by Dr. David Rubin from the University of Chicago. He is one of the leading gastroenterologists in the world, and was very involved in the...
See the DDW link below: The winners: 1) Rinvoq; 2) Xeljanz; 3) Stelara And it's not even close! The JAK inhibitors are winning. Also, if you look around in the E-Posters at DDW, you will find that...
Hi friends, Just thought I'd give an update for those who are interested in Rinvoq (Xeljanz is the sister medicine). The Good: The medicine works fast! This is day 21 without prednisone. Stools well...
When I was on Humira I was able to stop the enemas for about two years. Now I have just recently started a new medicine (Rinvoq) and am in the process of getting in remission. I am currently using...
I also had UC with a "patch" in the cecum. But I also had inflammation in the rectal area. I would suspect your sister also has inflammation on the left side, perhaps not very bad at the moment....
It may be time for a biologic like Remicade or Entyvio in addition to the Rowasa enemas. I was deadly afraid of these biologic medicines. But when you look at the research, they are extremely safe. I...
I have been on the sister medicine Rinvoq for 19 days: it's already working very well. I hope Xeljanz works for you....
Often UC starts at the bottom (i.e., rectal area) and moves up. But really the only way to tell is by having a colonoscopy. I would strongly encourage your sister to have a stools test called a...
As far as the research I have seen, probiotics don't work--except for VSL 3 that has been shown to help with pouchitis. Since your colitis is on the left side, you may want to try the mesalamine...
I doubt that diet alone is going to get you far. This is an autoimmune disease. Believe me, my family has had me try all kinds of diets for the last 20 years--they don't work, at least for me. Your...
Where is your colitis? Left-sided? Pan-colitis? Do you have mucus with the stools? It's difficult to give an answer without info....
Today is day 14 on this medication. I thought I'd give an update that may be useful for others. -My last flare was around March: I had developed a small number of antibodies to Humira and the Humira...
God's richest blessings to you, Songlady. Don't give up....
As a follow-up to my previous post: side-effects. Today I woke up with a bit of a sore throat which has improved throughout the day. Also, I have felt more fatigue than usual. Is this from the Rinvoq...
The journey on Rinvoq continues. Yesterday (day 4) I was actually a bit constipated and there was no bowel movement. I got a little nervous because for me constipation is sometimes related to...
Agree with the comments above. Prednisone is very toxic. Have your doctor up the Xeljanz....
No. And it's such a relief!...
If they lowered your dose, there is a slightly better than 50% chance of regaining remission if they raise the dose up again. See this video by Dr. David Rubin on JAK inhibitors: 'JAK Therapies:...
So I was on Humira but the trough levels were low and antibodies were higher than normal. Also, I had a calprotectin test that was about 6,000! I had noticed mucus in my stools and a bit of blood and...
Are you on any meds? What worked for me, at first, were the rectal mesalamine enemas. After a while, I needed to go on a biologic and we did Humira. I was terrified of the biologics, but then with...